The Potential Use of Neuroimaging Biomarkers in the Treatment of Obsessive-Compulsive Disorder

Opinion statement Predicting treatment outcome in obsessive-compulsive disorder (OCD) has become an important research priority given the prevalence and disability associated with the disorder and the fact that different effective treatments exist. Here, we summarize recent studies that have used neuroimaging to predict treatment outcome across three different treatment modalities: psychological treatment (exposure and response prevention), medication, and neurosurgery. Although several neural baseline variables have been shown to predict treatment outcome in OCD, results are so far not conclusive. We highlight some limitations from the current literature and offer some conceptual and methodological suggestions for future research.
Source: Current Treatment Options in Psychiatry - Category: Psychiatry Source Type: research