A Combination of Two Truncating Mutations in USH2A causes more Severe and Progressive Hearing Impairment in Usher syndrome type IIa.

CONCLUSIONS: The results have direct implications for patient counselling in terms of prognosis of hearing and may serve as baseline measures for future (genetic) therapeutic interventions. PMID: 27318125 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/27318125?dopt=Abstract

Source: Hearing Research - June 14, 2016 Category: Audiology Authors: Hartel BP, Löfgren M, Huygen PL, Guchelaar I, Lo-A-Njoe Kort N, Sadeghi AM, van Wijk E, Tranebjærg L, Kremer H, Kimberling WJ, Cremers CW, Möller C, Pennings RJ Tags: Hear Res Source Type: research