Suppressive effect of epigallocatechin‐3‐O‐gallate on endoglin molecular regulation in myocardial fibrosis in vitro and in vivo

In conclusion, epigallocatechin‐3‐O‐gallate (EGCG) attenuated the endoglin expression and myocardial fibrosis by anti‐inflammatory effect in vitro and in vivo, the novel suppressive effect was mediated through JNK/AP‐1 pathway.

Source: Journal of Cellular and Molecular Medicine - June 15, 2016 Category: Molecular Biology Authors: Chiu‐Mei Lin, Hang Chang, Bao‐Wei Wang, Kou‐Gi Shyu Tags: Original Article Source Type: research