Novel SCN10A variants associated with Brugada syndrome

Conclusion
In six BrS probands who carried SCN10A variants, most experienced severe arrhythmic attacks. It is of clinical importance to screen SCN10A mutations in BrS, although the functional significance of these variants remains unclear.

Source: Europace - June 12, 2016 Category: Cardiology Authors: Fukuyama, M., Ohno, S., Makiyama, T., Horie, M. Tags: Channelopathies Source Type: research