New NAS Members Mini-Symposium (1) Developing a deep understanding of the immune system, with an emphasis on 'system' (2) Adventures in evolutionary genomics: from comparison of the first bacterial genomes to a new generation of genome engineering tools

New NAS Members Mini-Symposium Drs. Ronald Germain and Eugene Koonin will deliver lectures at a mini-symposium that will be held to celebrate their recent election to the National Academy of Sciences. All are welcome to hear about the exciting research going on in their labs. The two join the more than 40 active NIH scientists in the academy. Germain is an NIH distinguished investigator in NIAID’s lymphocyte biology section. He studies the basic aspects of innate and adaptive immune function, with an emphasis on the biochemical mechanisms involved in the discrimination between self and foreign peptide-associated major histocompatibility complex molecules by T-cells as well as on T-cell antigen-presenting cell interactions and the subsequent delivery of effector function. Germain’s talk is titled “Developing a deep understanding of the immune system, with an emphasis on ‘system.’” Dr. Eugene Koonin is a senior investigator in the evolutionary genomics research group, National Library of Medicine/ National Center for Biotechnology Information. He performs research in many areas of evolutionary genomics and takes advantage of the advances in comparative genomics and systems biology to address fundamental problems in evolutionary biology. He hypothesized in 2005 that “spacer DNA” in the clustered regularly interspaced short palindromic repeats (CRISPR) loci of bacteria and Archaea, which matched sequences of bacteriophages, could be a key part of a sort of ada...
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