Iron Parameters Determine the Prognosis of Critically Ill Patients*

Conclusions: Our findings demonstrate that parameters of iron metabolism, particularly transferrin saturation, that reflect serum iron availability, are strong outcome predictors in ICU patients. These data suggest that a failure of iron homeostasis with increased iron availability in serum occurs in lethally ill ICU patients and should trigger prospective clinical trials evaluating the usefulness of iron-chelating therapy in critical illness and sepsis.
Source: Critical Care Medicine - Category: Emergency Medicine Tags: Clinical Investigations Source Type: research