National Study Reviews Drug Administration during CPR

SEATTLE (KING 5) - In addition to CPR, paramedics routinely administer drugs to get the patient stabilized before reaching the hospital.  But do those drugs really improve the chances of survival? That was unknown until now. A national study led by UW finally has an answer—which is—it depends. When a King County Medic One team arrives at the scene of a cardiac arrest. CPR is standard. So is lidocaine to stabilize heart rhythm. “These drugs have been around-- lidocaine for probably 50 years, amiodarone for more than ten years-- and we used them with the best intention of wanting to save lives. The reality is we never knew," said Medic One Medical Director Dr. Peter Kudenchuk. Read More Related on JEMS: In-Depth Summary of 2015 AHA Guidelines Updates for EMS Providers  Erin E. Brennan, MD , Steven Brooks, MD , Mark S. Link, MD , Robert E. O’Connor, MD, MPH , Eric Lavonas, MD , Farida Jeejeebhoy, MD , Diane L. Atkins, MD , Alan de Caen, MD , Marya L. Strand, MD, MS, FAAP , Henry C. Lee, MD, FAAP Strategies for the Prehospital Treatment of Stable Ventricular Tachycardia Eric Cortez, MD , Carla Cash, MD , David P. Keseg, MD, FACEP , Raymond L. Fowler, MD, FACEP    
Source: JEMS: Journal of Emergency Medical Services News - Category: Emergency Medicine Tags: News Cardiac & Resuscitation Source Type: news

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Pacing and Clinical Electrophysiology, Volume 0, Issue ja, -Not available-.
Source: Pacing and Clinical Electrophysiology : PACE - Category: Cardiology Authors: Tags: EDITORIAL ā€INVITED Source Type: research
Publication date: April 2019Source: Archives of Cardiovascular Diseases Supplements, Volume 11, Issue 2Author(s): V. Dubes, S. Charron Guitoger, C. Michel, M. Constantin, M. Haissaguerre, M. Hocini, O. Bernus, D. BenoistIntroductionThe right ventricular outflow tract (RVOT) is the main origin of idiopathic ventricular tachycardia (IVTs). Sympathetic stimulation is involved in IVTs but mechanisms underlying this preferential origin remain unknown.ObjectiveTo determine the role of ß1- and ß2-adrenergic receptors (ß1-AR, ß2-AR) in the regional modulation of right ventricular (RV) electrophysiological p...
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
ConclusionAlthough no serious rhythm disorders were found, ventricular dysrhythmias are frequent in patients one year after “infarct like” acute myocarditis, especially in those without complete recovery on CMR. This work highlights the importance of maintaining long-term FU in these patients, most of whom have normal LVEF.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
ConclusionEWI activation mapping can locate ventricular activation inside the left ventricular wall thickness and calculate the propagation of the wave front through the muscle. In the future, this technology might help to differentiate endocardial from epicardial VT during complex ablation procedures.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
ConclusionThis work enabled us to characterize two novel CPVT mutations, providing more insight into functional mechanisms involved in this pathology, and further validating the use of human pluripotent stem cells for investigating complex cardiac rhythm disorders.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
Abstract Background: Hypertrophic cardiomyopathy (HCM) is associated with sudden death (SD). Myocardial fibrosis is reportedly correlated with SD. Objective: We performed a systematic review with meta-analysis, updating the risk markers (RMs) in HCM emphasizing myocardial fibrosis. Methods: We reviewed HCM studies that addressed severe arrhythmic outcomes and the certain RMs: SD family history, severe ventricular hypertrophy, unexplained syncope, non-sustained ventricular tachycardia (NSVT) on 24-hour Holter monitoring, abnormal blood pressure response to exercise (ABPRE), myocardial fibrosis and left ventricular outflow t...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
Abstract Background: Hypertrophic cardiomyopathy (HCM) is associated with sudden death (SD). Myocardial fibrosis is reportedly correlated with SD. Objective: We performed a systematic review with meta-analysis, updating the risk markers (RMs) in HCM emphasizing myocardial fibrosis. Methods: We reviewed HCM studies that addressed severe arrhythmic outcomes and the certain RMs: SD family history, severe ventricular hypertrophy, unexplained syncope, non-sustained ventricular tachycardia (NSVT) on 24-hour Holter monitoring, abnormal blood pressure response to exercise (ABPRE), myocardial fibrosis and left ventricular outflow t...
Source: Arquivos Brasileiros de Cardiologia - Category: Cardiology Source Type: research
CONCLUSIONS: discordant shock advisements were observed for each AED and varied between manufacturers, most often involving VF. There may be implications for termination of resuscitation decision making. BACKGROUND: PMID: 30892980 [PubMed - as supplied by publisher]
Source: Prehospital Emergency Care - Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research
ConclusionThe S-ICD ™ seems to be a valuable option for the prevention of SCD in CAD patients. Patients with systemic infections of a transvenous ICD and, therefore, a need for an alternative might benefit from the absence of intracardiac leads as the S-ICD™ is safe and works flawlessly in these patients. Inadequat e shock delivery was very rare, while every episode of ventricular arrhythmia was terminated by the first shock.
Source: Clinical Research in Cardiology - Category: Cardiology Source Type: research
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Source: Clinical Toxicology - Category: Toxicology Authors: Source Type: research
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