Oscillating glucose induces microRNA-185 and impairs an efficient antioxidant response in human endothelial cells

Intracellular antioxidant response to high glucose is mediated by Cu/Mn-superoxide dismutases (SOD-1/SOD-2), catalase (CAT) and glutathione peroxidases (GPx), particularly glutathione peroxidase-1 (GPx-1). Alt...

Source: Cardiovascular Diabetology - April 30, 2016 Category: Cardiology Authors: Lucia La Sala, Monica Cattaneo, Valeria De Nigris, Gemma Pujadas, Roberto Testa, Anna R. Bonfigli, Stefano Genovese and Antonio Ceriello Source Type: research