Crohn's disease: Impaired bacterial clearance in IBD

Nature Reviews Gastroenterology & Hepatology 13, 251 (2016). doi:10.1038/nrgastro.2016.55 Author: Iain Dickson Patients with the neurodegenerative lysosomal lipid storage disorder Niemann-Pick disease type C1 (NPC1) can present with IBD, but the functional mechanism of this association was previously unclear. New findings now shed light on this link, showing that impaired induction of autophagy resulting in defective clearance

http://feeds.nature.com/~r/nrgastro/rss/current/~3/1_blRd4NkCs/nrgastro.2016.55

Source: Nature Reviews Gastroenterology and Hepatology - March 22, 2016 Category: Gastroenterology Authors: Iain Dickson Tags: Research Highlight Source Type: research

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