Health-related quality of life in multiple sclerosis: Direct and indirect effects of comorbidity
Conclusions:
Increased disability, depression and anxiety symptoms, fatigue, and physical comorbidity are associated with decreased HRQoL in MS. Disability most strongly diminishes HRQoL and, thus, interventions that reduce disability are expected to yield the most substantial improvement in HRQoL. Yet, interventions targeting other factors amenable to change, particularly depression but also anxiety, fatigue, and physical comorbidities, may all result in meaningful improvements in HRQoL, as well. Our findings point to the importance of further research confirming the efficacy of such interventions.
Source: Neurology - Category: Neurology Authors: Berrigan, L. I., Fisk, J. D., Patten, S. B., Tremlett, H., Wolfson, C., Warren, S., Fiest, K. M., McKay, K. A., Marrie, R. A., For the CIHR Team in the Epidemiology and Impact of Comorbidity on Multiple Sclerosis (ECoMS) Tags: Quality of life, All Psychiatric disorders, Depression, Multiple sclerosis ARTICLE Source Type: research
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