Developing ways to study influenza D virus

Researchers have found antibodies to the newly discovered influenza D virus in pigs, cattle, horses, goats and sheep, but not poultry. A researcher has proven that the guinea pig can be used as an animal model and is developing a way to study the virus in living cells—trachea and lung epithelial cells from swine and cattle.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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On 22 June 2020, the International Health Regualtions (IHR) Focal Point (FP) of Brazil shared a preliminary report with the Panamerican Health Organization, the WHO Regional Office for the Americas of a human infection withInfluenza A(H1N2) variant virus (A(H1N2)v). According to the report, the patient, a 22-year-old female, with no comorbidities, worked in a swine slaughterhouse in Ibipor ã Municipality, Paraná State, and developed an influenza-like illness on 12 April 2020. The patient initially sought medical care on 14 April and a respiratory specimen was obtained on 16 April as part of routine surveillan...
Source: WHO Disease Outbreaks - Category: Infectious Diseases Tags: news Source Type: news
AbstractInfluenza A viruses evolve rapidly to escape host immunity. In swine, this viral evolution has resulted in the emergence of multiple H1 and H3 influenza A virus (IAV) lineages in the United States (US) pig populations. The heterologous prime-boost vaccination strategy is a promising way to deal with diverse IAV infection in multiple animal models. However, whether or not this vaccination strategy is applicable to US swine to impart immunity against infection from North American strains of IAV is still unknown. We performed a vaccination-challenge study to evaluate the protective efficacy of using multivalent inacti...
Source: Veterinary Research - Category: Veterinary Research Source Type: research
TWiV reviews a new H1N1 swine influenza virus from China with pandemic potential, Ad5 vectored SARS-CoV-2 oral vaccine candidate, Operation Warp Speed vaccine candidates, FDA guidance on vaccine approval, and answer listener email. Click arrow to playDownload TWiV 634 (72 MB .mp3, 120 min)Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Show notes at microbe.tv/twiv
Source: virology blog - Category: Virology Authors: Tags: This Week in Virology adenovirus COVID-19 FDA vaccine guidance Operation Warp Speed SARS-CoV-2 viral viruses Source Type: blogs
A new study warns that the strain of H1N1, common on China ’s pig farms since 2016, should be “urgently” controlled to avoid another pandemic.
Source: NYT Health - Category: Consumer Health News Authors: Tags: China Pigs Swine Influenza Proceedings of the National Academy of Sciences Source Type: news
An influenza virus identified in pigs in China has a concerning mix of genes, but experts say there is no way to know if it will evolve to be transmissible between humans.
Source: The Scientist - Category: Science Tags: News & Opinion Source Type: news
This influenza virus strain has been circulating among the swine population in China over the past several years and has infected some humans.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Tags: Healthcare /healthcare Innovation /innovation Science /science Editors' Pick editors-pick business pharma Source Type: news
Pandemic influenza A viruses can emerge from swine, an intermediate host that supports adaptation of human-preferred receptor-binding specificity by the hemagglutinin (HA) surface antigen. Other HA traits necessary for pandemic potential are poorly understood. For swine influenza viruses isolated in 2009 –2016, gamma-clade viruses had less stable HA proteins (activation pH 5.5–5.9) than pandemic clade (pH 5.0–5.5). Gamma-clade viruses replicated to higher levels in mammalian cells than pandemic clade. In ferrets, a model for human adaptation, a relatively stable HA protein (pH 5.5–5.6) was n ecessar...
Source: eLife - Category: Biomedical Science Tags: Microbiology and Infectious Disease Source Type: research
Conclusions: The speed of the emergency responses to H1N1 was faster than COVID-19, which might be an important influential factor for slowing down the arrival of the peak time at the beginning of the epidemic. Although COVID-19 in China is coming to an end, the government should improve the public health emergency system, in order to control the spread of the epidemic and lessen the adverse social effects in possible future outbreaks.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Read Fast Facts from CNN about the H1N1 influenza virus, also known as swine flu. There was a global outbreak which lasted from 2009 to 2010.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
AbstractUnderstudied, coinfections are more frequent in pig farms than single infections. In pigs, the term “Porcine Respiratory Disease Complex” (PRDC) is often used to describe coinfections involving viruses such as swine Influenza A Virus (swIAV), Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), and Porcine CircoVirus type 2 (PCV2) as well as bacteria likeActinobacillus pleuropneumoniae,Mycoplasma hyopneumoniae andBordetella bronchiseptica. The clinical outcome of the various coinfection or superinfection situations is usually assessed in the studies while in most of cases there is no clear eluci...
Source: Veterinary Research - Category: Veterinary Research Source Type: research
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