Eosinophilic esophagitis after desensitization to dust mites with sublingual immunotherapy

Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder characterized by esophageal dysfunction and eosinophilic infiltration of the esophageal mucosa. The disease affects both children and adults, with a prevalence of 5 per 10,000 inhabitants in Europe and the United States.1 Childhood cases are generally diagnosed between 5 and 10 years of age and adult cases between 30 and 40 years of age. The male-female sex ratio is 3:1 in a published series.2 The symptoms vary according to the age of the individual and consist of difficulties in feeding and in gaining weight in small children, abdominal pain and vomiting in older children, and solid food dysphagia and symptoms that suggest gastroesophageal reflux in adults.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letter Source Type: research