Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease

Conclusions CD4+CD25+CD127loCD45RA+ Tregs may be the most appropriate population from which to expand Tregs for autologous Treg therapy for CD, paving the way for future clinical trials.

http://gut.bmj.com/cgi/content/short/65/4/584?rss=1

Source: Gut - March 9, 2016 Category: Gastroenterology Authors: Canavan, J. B., Scotta, C., Vossenkämper, A., Goldberg, R., Elder, M. J., Shoval, I., Marks, E., Stolarczyk, E., Lo, J. W., Powell, N., Fazekasova, H., Irving, P. M., Sanderson, J. D., Howard, J. K., Yagel, S., Afzali, B., MacDonald, T. T., Hernan Tags: Crohn's disease, Open access Inflammatory bowel disease Source Type: research