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Novocure wins reimbursement from Humana for Optune brain cancer device

NovoCure (NSDQ:NVCR) said today it won reimbursement from Humana for treatments with its Optune device for patients with recurrent glioblastoma. The Optune is a mobile device that delivers low-intensity, intermediate frequency, alternating electric fields, referred to as “tumor treating fields,” to inhibit cancer cell replication and cause cancer cell death. The new reimbursement win brings the number of commercial payers covering Optune treatment up to 9, NovoCure said in a press release. In January, NovoCure said  it applied for a supplemental pre-market approval from the FDA for the 2nd generation of its Optune device for treating glioblastoma, a form of brain cancer. The FDA approved Optune’s 1st iteration in April 2011. NovoCure said it pared the weight of the newer version, which hit the European market last October, from 6 pounds to 2.7 pounds using digital signal generation technology. Last December, NovoCure touted positive data from a pivotal Phase III trial of the Optune device in combination with standard-of-care temozolomide for treating newly diagnosed glioblastoma, which was halted early for success. The post Novocure wins reimbursement from Humana for Optune brain cancer device appeared first on MassDevice.
Source: Mass Device - Category: Medical Equipment Authors: Tags: Business/Financial News Oncology NovoCure Source Type: news

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Abstract Glioblastoma multiforme (GBM), the most common and aggressive primary brain tumor, has a high mortality rate despite extensive efforts to develop new treatments. GBM exhibits both intra- and intertumor heterogeneity, lending to resistance and eventual tumor recurrence. Large-scale genomic and proteomic analysis of GBM tumors has uncovered potential drug targets. Effective and "druggable" targets must be validated to embark on a robust medicinal chemistry campaign culminating in the discovery of clinical candidates. Here, we review recent developments in GBM drug discovery and delivery. To identi...
Source: Pharmacological Reviews - Category: Drugs & Pharmacology Authors: Tags: Pharmacol Rev Source Type: research
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Source: Journal of Immunotherapy - Category: Allergy & Immunology Tags: Clinical Studies Source Type: research
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(FECYT - Spanish Foundation for Science and Technology) Spanish epidemiologists and geologists have found associations between esophageal cancer and soils where lead is abundant, lung cancer and terrains with increased copper content, brain tumor with areas rich in arsenic, and bladder cancer with high cadmium levels. These statistical links do not indicate that there is a cause-effect relationship between soil type and cancer, but they suggest that the influence of metals from the earth's surface on the geographical distribution of tumors should be analyzed.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
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This article originally appeared on Health.com
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Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Carcinogenesis and Cancer Genetics Source Type: research
(Georgia Institute of Technology) Cancer immune cell therapy has made headlines with astounding successes like saving former US President Jimmy Carter from brain cancer. But immunotherapy has also had many tragic flops. Georgia Tech researchers working to optimize the innovative treatment have implanted a genetic switch that activates T-cells when they are inside of tumors. Remote-control light waves resembling those used in a TV remote combine with gold nanorods to flip the switch.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
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