Dramatic Improvement in Juvenile Parkinsonism after Levodopa Treatment in a Patient Negative for the Mutation

Juvenile parkinsonism is a rare movement disorder. In pediatric patients, the manifestations are more complex and varied, which makes the diagnosis challenging. It may occasionally manifest as another disease such as dopa-responsive dystonia, Wilson disease, or neurodegeneration with brain iron accumulation (i.e., Hallervorden–Spatz disease).1,2 This paper reports a 14-year-old girl who experienced a variety of movement disorders such as parkinsonism and dystonia. Her symptoms changed and worsened within a few years, but dramatically improved with levodopa treatment.
Source: Pediatrics and Neonatology - Category: Perinatology & Neonatology Authors: Tags: Brief communication Source Type: research