Attenuation of hyperglycemia-induced apoptotic signaling and anti-angiogenic milieu in cultured cytotrophoblast cells.

CONCLUSION: Hyperglycemia induced apoptotic and anti-angiogenic signaling in CTBs. The observed diminution of hyperglycemia-induced signaling by SB203580 or rosiglitazone pretreatment suggests the involvement of apoptotic and anti-angiogenic signaling in CTB dysfunction.
PMID: 26930265 [PubMed - as supplied by publisher]

Source: Hypertension in Pregnancy - March 3, 2016 Category: OBGYN Tags: Hypertens Pregnancy Source Type: research