Comprehensive analysis of DNA methylation and gene expression of placental tissue in preeclampsia patients.

CONCLUSION: Our study is the first study to determine the genome-wide DNA methylation patterns in preeclampsia placenta using microarrays. The results revealed that clusters of DNA methylation were aberrantly altered in preeclampsia placenta compared with controls, which indicated misregulation of DNA methylation. PMID: 26910130 [PubMed - as supplied by publisher]
Source: Hypertension in Pregnancy - Category: OBGYN Tags: Hypertens Pregnancy Source Type: research