Designing to Succeed

The finalists for this year’s Most Valuable Patient Initiative or Service at the 2016 eyeforpharma Barcelona Awards showcase the potential for impact when patients become collaborators in design. Understanding the human aspects of living with a condition is in many ways less straightforward than drug development. Everyone experiences their health challenges differently, and it’s clear this can’t be designed for in a lab. That’s why collaborating with the patient brings benefits. Here are three lessons we learned from this year’s crop of patient innovators:  1. Ongoing engagement with the patient makes iterative design possible, ideal for mHealth projects, where it is relatively easy to deploy updates through app store and Google Play. Merck deployed this strategy to great effect in the product development of their app ‘Second Voice’, an inspiring use of tech to help patients with difficulty speaking. Patients can use the app to quickly draw on over 130 pre-programmed messages, including dedicated messages to communicate pain, or they are even able to add their own. By listening to patient needs and designing a tool that helps in both a clinical and home setting, Merck have created a tool that really resonates with patients; it has hit 2,500 downloads in just two months.  In a similar vein, the team behind Roche’s diabetes app, Gluci-Chek, which quickly analyses the carbohydrate intake of meals, paneled patien...
Source: EyeForPharma - Category: Pharmaceuticals Authors: Source Type: news

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This study examined 103 patients with bipolar 1 disorder who, despite taking a mood stabilizer, experienced frequent relapses. During a 12-month period, the group receiving cognitive therapy had significantly fewer bipolar episodes and reported less mood symptoms on the monthly mood questionnaires. They also had less fluctuation in manic symptoms. It’s normal to panic in the days and weeks your symptoms return; however, as you can see, there are many options to pursue. If the first approach doesn’t work, try another. Persevere until you achieve full remission and feel like yourself again. It will happen. Trust me on that.
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Antidepressant Bipolar Depression General Medications Manic Episode Mood Disorder Mood Stabilizer Relapse Source Type: blogs
After reading the Danish digital health strategy, one of the most forward-looking examples of a government-supported objective to adjust the medical arena to the 21st century, we looked around what real-life projects aim to transform patients’ and doctors’ lives for the better in the Scandinavian country. Our findings are thrilling: the newly established Danish National Genome Center strives to have at least 60,000 whole-genome sequenced in the next 5 years, while the Copenhagen Healthtech Cluster wants to set up a network of data registers updated so fast that it might enable helping doctors real-time – ...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine Healthcare Policy big data Danish Denmark digital health digital health strategy genetics genomics health data healthcare design Innovation technology Source Type: blogs
In a blog post last week, I shared an excerpt from the new book that Paul Cerrato and I just completed,The Transformative Power of Mobile Medicine. Here is a second excerpt from Chapter 3,  “Exploring the Strengths and Weaknesses of Mobile Health Apps.”Even patients who are fully engaged in their own care still need access to medical apps they can trust. The IQVIA Institute for Human Data Science has performed a detailed analysis of the clinical evidence supporting mobile health apps, rating their maturity and relative quality. Its rating scale places a single observational study near the bottom of th...
Source: Life as a Healthcare CIO - Category: Information Technology Source Type: blogs
Introduction to the Theme "New Therapeutic Targets". Annu Rev Pharmacol Toxicol. 2019 Jan 06;59:15-20 Authors: Insel PA, Amara SG, Blaschke TF, Meyer UA Abstract "New Therapeutic Targets" is the theme of articles in the Annual Review of Pharmacology and Toxicology, Volume 59. Reviews in this volume discuss targets for a variety of conditions in need of new therapies, including type 2 diabetes, heart failure with preserved ejection fraction, obesity, thyroid-associated ophthalmopathy, tinnitus, multiple sclerosis, Parkinson's disease and other neurodegenerative diseases, pain, depre...
Source: Annual Review of Pharmacology and Toxicology - Category: Drugs & Pharmacology Authors: Tags: Annu Rev Pharmacol Toxicol Source Type: research
In conclusion, we found a gradient of increasing blood pressure with higher levels of BMI. The fact that this gradient is present even in the fully adjusted analyses suggests that BMI may cause a direct effect on blood pressure, independent of other clinical risk factors. PRRX1 as a Possible Point of Control for Remyelination https://www.fightaging.org/archives/2018/12/prrx1-as-a-possible-point-of-control-for-remyelination/ Researchers here outline what is possibly a new point of intervention in the processes that maintain the myelin sheath that wraps nerves. This sheath is vital to the correct operatio...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
This study compared utilization patterns of high-cost services and medications for patients receiving care from Accountable Care Organization (ACO)-participating physicians and those receiving care from non-ACO physicians during the initial phases of ACO development in a commercially insured environment. Patients ≥18 years (≥40 years for chronic obstructive pulmonary disease [COPD]) with prevalent rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis, type 2 diabetes, COPD, or chronic low back pain between January 1, 2012, and August 31, 2014 were identified in the HealthCore Integrated Research Databa...
Source: Pain Physician - Category: Anesthesiology Authors: Tags: Popul Health Manag Source Type: research
ConclusionMGUS is often incidentally detected as part of a work up for other medical conditions, and our results reveal that there is a variety of reasons for which monoclonal testing is performed. With recent developments in our understanding of the significance of monoclonal gammopathy and its association with certain renal and organ damage (Fermand et al., 2018; Leung et al., 2012), there may be a change in how the paraproteinemia investigations are utilized by clinicians in different disciplines. It will be important to recognize and establish appropriate indications for testing. Furthermore, MGUS patients present with...
Source: Blood - Category: Hematology Authors: Tags: 651. Myeloma: Biology and Pathophysiology, excluding Therapy: Poster III Source Type: research
There are plenty of reasons to never allow a bagel, sandwich, or pretzels to cross your lips again. But here are the top 10 most powerful and compelling reasons to tell the USDA and other providers of dietary advice to bug off with their “healthy whole grains” nonsense. Gliadin-derived opioid peptides (from partial digestion to 4- and 5-amino acid long fragments) increase appetite substantially–as do related proteins from rye, barley, and corn. This is a big part of the reason why grains make you gain weight. Gliadin-derived opioid peptides are mind active drugs that trigger behavioral outbursts in kids ...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates autoimmune blood sugar Gliadin gluten gluten-free grain-free grains Inflammation joint pain low-carb wheat belly Source Type: blogs
In the course of many nurses'healthcare careers, witnessing the illness, suffering, and death of others is commonplace. From dialysis and med-surg to home health and the ICU, nurses create therapeutic relationships with patients and their families, providing spiritual and emotional comfort, compassion, and expert skilled care based on many decades of nursing science and evidence-based interventions.Aside from witnessing the challenges faced by others, nurses are themselves human beings with their own life experiences, victories, and suffering. How a nurse navigates their own personal suffering plays a role in determining h...
Source: Digital Doorway - Category: Nursing Tags: healthcare nurse nurses nursing Source Type: blogs
Cannabis is the one growth industry in the U.S. that you can count on. Recreational use of marijuana is now legal in many states. Moreover, there's increasing attention being paid to the medical uses of cannabis-based products. An Israeli lab has been set up to provide clinical validation for cannabis medical research (see:Israeli lab set up to give clinical validation to cannabis research). Below is an excerpt from an article on this topic:Israeli firm Asana Bio Group Ltd. has invested $2.3 million in a lab that will provide clinical trial services to companies that are developing a wide range of medica...
Source: Lab Soft News - Category: Laboratory Medicine Authors: Tags: Clinical Lab Industry News Clinical Lab Testing Healthcare Innovations Lab Industry Trends Medical Research Pharmaceutical Industry Source Type: blogs
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