Association of SLCO2B1 Genotypes With Time to Progression and Overall Survival in Patients Receiving Androgen-Deprivation Therapy for Prostate Cancer [Urologic Oncology]

Conclusion The association of SNP rs1077858 with OS may be a result of differential SLCO2B1 expression and the consequent increased uptake of DHEAS and subsequent resistance to ADT, which, in turn, may contribute to decreased OS.
Source: Journal of Clinical Oncology - Category: Cancer & Oncology Authors: Tags: Statistical Genetics Urologic Oncology Source Type: research