Clinicopathologic Effect of DNMT3A Mutation in Adult T-Cell Acute Lymphoblastic Leukemia.

CONCLUSION: DNMT3A is frequently mutated in T-ALL and is associated with distinct clinicopathologic entities and a poor prognosis. These findings could help in risk stratification and treatment decisions for patients with T-ALL.
PMID: 26711182 [PubMed - in process]

Source: Clinical Lymphoma and Myeloma - January 1, 2016 Category: Cancer & Oncology Authors: Aref S, El Menshawy N, El-Ghonemy MS, Zeid TA, El-Baiomy MA Tags: Clin Lymphoma Myeloma Leuk Source Type: research