P21 (Waf1/Cip1) plays a critical role in furazolidone-induced apoptosis in HepG2 cells through influencing the caspase-3 activation and ROS generation.

In conclusion, these findings demonstrated that p21 plays a critical role in FZD-induced apoptosis in HepG2 cells through influencing the caspase-3 activation and ROS generation. PMID: 26687534 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26687534?dopt=Abstract

Source: Food and Chemical Toxicology - December 10, 2015 Category: Food Science Authors: Deng S, Tang S, Dai C, Zhou Y, Yang X, Li D, Xiao X Tags: Food Chem Toxicol Source Type: research

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