Cortical thickness mediates the effect of {beta}-amyloid on episodic memory

Conclusion:
These results suggest strong links among Aβ, cortical thickness, and memory. They highlight that, in individuals without dementia, vascular risk also contributes to cortical thickness and influences the relationships among Aβ, cortical thickness, and memory.

Source: Neurology - March 3, 2014 Category: Neurology Authors: Villeneuve, S., Reed, B. R., Wirth, M., Haase, C. M., Madison, C. M., Ayakta, N., Mack, W., Mungas, D., Chui, H. C., DeCarli, C., Weiner, M. W., Jagust, W. J. Tags: MRI, PET, All Cerebrovascular disease/Stroke, Memory, Alzheimer's disease ARTICLE Source Type: research