Shear-Activated Nanoparticle Aggregates Combined With Temporary Endovascular Bypass to Treat Large Vessel Occlusion [Basic Sciences]

Conclusions—
A novel intra-arterial, nanoparticle-based thrombolytic therapy combined with TEB achieves high rates of complete recanalization. Moreover, this approach reduces vascular trauma as compared with stent-retriever thrombectomy.

Source: Stroke - November 23, 2015 Category: Neurology Authors: Marosfoi, M. G., Korin, N., Gounis, M. J., Uzun, O., Vedantham, S., Langan, E. T., Papa, A.-L., Brooks, O. W., Johnson, C., Puri, A. S., Bhatta, D., Kanapathipillai, M., Bronstein, B. R., Chueh, J.-Y., Ingber, D. E., Wakhloo, A. K. Tags: Animal Models of Human Disease, Angiography, Treatment, Cerebrovascular Disease/Stroke Basic Sciences Source Type: research