Altered expression of keratin 14 in lesional epidermis of autoimmune skin diseases

ConclusionWe show focal loss of K14 in the basal epidermis correlating with interface dermatitis and hair follicle involvement. Moreover, enhanced reactivity of sera of patients with atopic dermatitis with K14 suggests K14 may function as an autoantigen in ASD.

Source: International Journal of Dermatology - November 6, 2015 Category: Dermatology Authors: Xiaoying Wei, Katharina Fricker, Alexander H. Enk, Eva N. Hadaschik Tags: Report Source Type: research