Combination of zoledronic acid and serine/threonine phosphatase inhibitors induces synergistic cytotoxicity and apoptosis in human breast cancer cells via inhibition of PI3K/Akt pathway

In conclusion, synergistic apoptotic effect of the combination treatment is correlated with the block of the PI3K/Akt signal pathway in breast cancer cells.

http://link.springer.com/10.1007/s13277-015-3265-x

Source: Tumor Biology - October 13, 2015 Category: Cancer & Oncology Source Type: research