Inhibition of Ras-mediated signaling pathways in CML stem cells

Conclusions A closer investigation of the influence of Ras-mediated signaling pathways on CML progression to blast crisis is warranted to uncover new directions for targeted therapies, particularly in cases that are resistant to current tyrosine kinase inhibitors.

http://link.springer.com/10.1007/s13402-015-0248-2

Source: Cellular Oncology - October 12, 2015 Category: Cancer & Oncology Source Type: research