Preterm Rabbit Model of Glycerol-Induced Intraventricular Hemorrhage

Intraventricular hemorrhage (IVH) remains a major complication of prematurity. We have developed a model of IVH in preterm rabbit pups. We deliver rabbit pups prematurely by C-section at 29-day gestational age (term = 32 days) and inject intraperitoneal glycerol at 3 h age to induce IVH. About 80 % of glycerol-treated pups develop IVH within 8 h age, which can be detected accurately with head ultrasound. These pups are reared in an infant incubator and gavage fed. At postnatal day 14, they exhibit hypomyelination, gliosis, and impaired neurological function. Hence, this is a novel animal model of IVH that can be used to test strategies to prevent post-hemorrhagic complication of IVH.
Source: Springer protocols feed by Neuroscience - Category: Neuroscience Source Type: news

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CONCLUSION: An increased uterine artery mean PI appears to be moderately useful in predicting perinatal death in pregnancies with suspected SGA. This article is protected by copyright. All rights reserved. PMID: 31785172 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
AbstractBackgroundTo investigate the effect of fetal sex on fibroids ’ growth during pregnancy according to the hCG serum levelsMethodsObservational study conducted from January 2007 to December 2016 on women with ultrasound identification of uterine fibroids who had a pregnancy within 1 year from diagnosis. The fibroids diameter was determined during the pre-pregnancy ultrasound, early first trimester (5 –7 weeks), late first trimester (11–13 weeks), second trimester (19–21 weeks), and third trimester (31–33 weeks). The diameter growth was calculated in each interval between two ultrasounds. ...
Source: Biology of Sex Differences - Category: Biology Source Type: research
This study was performed to compare analgesic outcomes after cesarean section. At a hospital in Southwestern Uganda where this study was undertaken, most of the basic postoperative nursing care after cesarean section is provided by family or friends of the patient. The current study was performed to compare outcomes when intrathecal morphine or transversus abdominis plane (TAP) block was used to provide postcesarean pain control in a resource-limited setting.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Anesthesia and Analgesia: Postoperative Analgesia Source Type: research
ConclusionKagami –Ogata syndrome should have been suspected because of the presence of polyhydramnios and omphalocele during pregnancy. Respiratory insufficiency soon after birth, because of a small thorax, is expected in this disease and a diagnosis during pregnancy may have enabled appropriate care after birth.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Conditions:   Caesarean Section;   Pain, Acute Interventions:   Drug: Bupivacaine Hcl 0.25% Inj;   Drug: saline 0.9% Sponsor:   Ataturk University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: Journal of Maternal-Fetal and Neonatal Medicine - Category: Perinatology & Neonatology Authors: Source Type: research
Conclusion: Patients with uterine fibroids with post-operative susceptibility artifacts in the near-field can be successfully treated with MRgFUS. PMID: 31709842 [PubMed - in process]
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
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