Renal physiology: Aldosterone-dependent NCC activation

Nature Reviews Nephrology 11, 567 (2015). doi:10.1038/nrneph.2015.145 Author: Ellen F. Carney A new study has identified a mechanism linking aldosterone to activation of the NaCl cotransporter (NCC), which has important roles in renal sodium reabsorption and blood-pressure homeostasis. “Aldosterone is a potent NCC activator, but the mechanism by which it interfaces with the WNK kinase pathway
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Authors: Tags: Research Highlight Source Type: research