Hyperpigmentation and atrophy in folds as cutaneous manifestation in a case of mitochondrial myopathy.
Hyperpigmentation and atrophy in folds as cutaneous manifestation in a case of mitochondrial myopathy.
Dermatol Online J. 2015;21(5)
Authors: Campuzano-Garcia AE, Rodriguez-Arambula A, Torres-Alvarez B, Castanedo-Casares JP
Abstract
Mitochondrial myopathies are inborn metabolism defect diseases manifested by symptoms reflecting failure of the final step in the mitochondrial respiratory chain. Clinical expression of these conditions can vary widely, but typically includes organ systems with a high energy demand, such as striated muscle, myocardium, and nervous and liver tissues. In contrast, cutaneous manifestations are rare and are non-specific, most commonly presenting as pigmentation disorders. In this case report, we present a case of Alpers syndrome accompanied by hyperpigmentation and atrophy in skin folds.
PMID: 26295861 [PubMed - as supplied by publisher]
Source: Dermatol Online J - Category: Dermatology Authors: Campuzano-Garcia AE, Rodriguez-Arambula A, Torres-Alvarez B, Castanedo-Casares JP Tags: Dermatol Online J Source Type: research
More News: Dermatology | Liver | Mitochondrial Disease | Respiratory Medicine | Skin | Urology & Nephrology