Sputum high mobility group box-1 in asthmatic children: a noninvasive sensitive biomarker reflecting disease status.

CONCLUSION: The present study provides evidence that sputum HMGB1 is a sensitive biomarker of allergic asthma in children because it was increased and correlated directly with asthma severity and inversely with lung function indices.
PMID: 26250770 [PubMed - in process]

Source: Annals of Allergy, Asthma and Immunology - August 1, 2015 Category: Allergy & Immunology Authors: Cuppari C, Manti S, Chirico V, Caruso R, Salpietro V, Giacchi V, Laganà F, Arrigo T, Salpietro C, Leonardi S Tags: Ann Allergy Asthma Immunol Source Type: research