Ambient air pollution and adverse birth outcomes: a natural experiment study

Background:
Radical regulations to improve air quality, including traffic control, were implemented prior to and during the 2008 Beijing Olympic Games. Consequently, ambient concentrations of nitrogen dioxide (NO
2
) and particular matter 10 micrometers or less (PM
10
), were reduced in a distinct and short window of time, which presented a natural experiment for testing the relationships between maternal exposure to PM
10
and NO
2
during pregnancy and adverse birth outcomes.
Methods:
We estimated the effect of PM
10
and NO
2
exposure during each trimester of gestation on the risk of preterm birth among live births and the birth weight among term babies. The data were based on 50,874 live births delivered between January 1, 2006 and December 31, 2010 at the Beijing Haidian Maternal and Child Health Hospital. Air monitoring data for the same period were obtained from the Beijing Municipal Environmental Monitoring Center.
Results:
Among full-term births, maternal exposure to NO
2
in the third trimester predicted birth weight, with each 10-unit increment (per 10 ug/m
3
) in NO
2
concentration associated with a ...

Source: Population Health Metrics - July 18, 2015 Category: Epidemiology Authors: Cheng HuangCatherine NicholsYang LiuYunping ZhangXiaohong LiuSuhong GaoZhiwen LiAiguo Ren Source Type: research