PNPLA3, obesity and heavy alcohol use in cirrhosis patients may exert a synergistic increase hepatocellular carcinoma risk

We examined whether germline susceptibility to hepatic steatosis not only independently predisposes to HCC but may also act synergistically with other risk factors.

Source: Clinical Gastroenterology and Hepatology - May 8, 2024 Category: Gastroenterology Authors: Aaron P. Thrift, Fasiha Kanwal, Hyeyeun Lim, Hao Duong, Yanhong Liu, Amit G. Singal, Saira Khaderi, Sumeet K. Asrani, Christopher I. Amos, Hashem B. El-Serag Source Type: research