ISMRM: MRI technique has value in identifying triple-negative breast cancer

SINGAPORE -- A quantitative MRI technique called 3D amide proton transfer imaging (3D-APT) can help in distinguishing between triple-negative and non-triple-negative breast cancer, according to research presented May 6 at the International Society for Magnetic Resonance in Medicine (ISMRM) 2024 meeting. Saiqun Lyu from the Affiliated Hospital of Chengdu University in China said that 3D-APT demonstrated higher transfer values in triple-negative breast cancer patients. Additionally, 3D-APT’s value was further augmented by the addition of diffusion-weighted imaging (DWI). “These findings hold significant value as a crucial point of reference for developing individualized treatment strategies and assessing prognosis in clinical practice,” Lyu and colleagues highlighted. Triple-negative breast cancer is highly aggressive, prone to recurrence, and tied to a poorer prognosis than other breast cancer types. This means that accurate identification of these cancers is important for treatment decisions and prognosis assessment. Advanced imaging techniques have been explored in this area, including 3D-APT and DWI. 3D-APT is a quantitative imaging technique that can noninvasively detect amide protons in endogenous low-concentration proteins and peptides. This reflects their concentration and environmental changes. However, Lyu said there are still aspects of molecular subtyping from these imaging techniques that have not yet been explored. Lyu and colleagues studied the poten...
Source: AuntMinnie.com Headlines - Category: Radiology Authors: Tags: ISMRM 2024 Source Type: news