Exercise promotes osteogenic differentiation by activating the long non-coding RNA H19/microRNA-149 axis

CONCLUSION: Appropriate treadmill exercise can effectively stimulate bone formation and promote the increase of bone density and bone volume in growing mice, thus enhancing the peak bone mass of mice. The lncRNA H19/miR-149 axis plays an important regulatory role in osteogenic differentiation.PMID:38680671 | PMC:PMC11045468 | DOI:10.5312/wjo.v15.i4.363

Source: World Journal of Orthopaedics - April 29, 2024 Category: Orthopaedics Authors: Xu-Chang Zhou Dong-Xue Wang Chun-Yu Zhang Ya-Jing Yang Ruo-Bing Zhao Sheng-Yao Liu Guo-Xin Ni Source Type: research