Overexpression of YTHDF3 increases the specific productivity of the recombinant protein in CHO cells by promoting the translation process

In conclusion, the findings in this study provide a novel approach for mammalian cell engineering to increase protein productivity by regulating m6A.PMID:38651251 | DOI:10.1002/biot.202400078

Source: Biotechnology Journal - April 23, 2024 Category: Biotechnology Authors: Zhao-Ming Cui Ying-Ying Feng Yan-Ping Gao Hai-Tong Wang Jiang-Tao Lu Jia-Liang Guo Hong-Yan Xu Le-le Qiu Tian-Yun Wang Yan-Long Jia Source Type: research