Selenoprotein W engages in overactive osteoclast differentiation in multiple myeloma

CONCLUSION: Our findings suggest a possibility that feedforward signaling of osteoclastogenic SELENOW by TNFα derived from multiple myeloma induces overactive osteoclast differentiation, leading to bone loss during multiple myeloma.PMID:38683225 | PMC:PMC11058866 | DOI:10.1007/s11033-024-09517-2

Source: Molecular Biology Reports - April 29, 2024 Category: Molecular Biology Authors: Hyunsoo Kim Jiin Oh Min Kyoung Kim Kyung Hee Lee Daewon Jeong Source Type: research