Optimal hippocampal targeting in responsive neurostimulation for mesial temporal lobe epilepsy

CONCLUSIONS: Dual unilateral hippocampal implantation increased RNS contact density in patients with unilateral MTLE, which contributed to improved outcomes, not by stimulating more of the hippocampus, but instead by being more likely to stimulate a latent subtarget in the anterior hippocampus. It remains to be explored whether a single electrode targeted selectively to this region would also result in improved outcomes.PMID:38669705 | DOI:10.3171/2024.2.JNS231732

Source: Journal of Neurosurgery - April 26, 2024 Category: Neurosurgery Authors: Henry M Skelton Katie Bullinger Faical Isbaine Jonathan C Lau Jon T Willie Robert E Gross Source Type: research