Structure-based drug design of DNA minor groove binders and evaluation of their antibacterial and anticancer properties
This study shed light on the mechanism of action of MGBs and revealed the important structural features for their antitumor and antibacterial activities, which are important to guide future development of MGB derivatives as novel antibacterial and anticancer agents.PMID:38678825 | DOI:10.1016/j.ejmech.2024.116440
Source: European Journal of Medicinal Chemistry - Category: Chemistry Authors: Hasan Y Alniss Hadeel M Al-Jubeh Yousef A Msallam Ruqaiyyah Siddiqui Zinb Makhlouf Anil Ravi Rania Hamdy Sameh S M Soliman Naveed A Khan Source Type: research