Frontoparietal beta event characteristics are associated with early life stress and psychiatric symptoms in adults

This study sought to examine whether features of beta events over frontoparietal electrodes were associated with early life stress (ELS) and the related clinical presentation. Eighteen adults with documented ELS (n = 18; ELS + ) and eighteen adults without documented ELS (n = 18; ELS-) completed eyes-closed resting state EEG as part of their participation in a larger childhood stress study. The rate, power, duration, and frequency span of transient oscillatory events were calculated within the beta band at five frontoparietal electrodes. ELS variables were positively associated with beta event rate at Fp2 and beta event duration at Pz, in that greater ELS was associated with higher resting rates and longer durations. These beta event characteristics were used to successfully distinguish between ELS + and ELS- groups. In an independent clinical dataset (n = 25), beta event power at Pz was positively correlated with ELS. Beta events deserve ongoing investigation as a potential disease marker of ELS and subsequent psychiatric treatment outcomes.PMID:38670050 | DOI:10.1016/j.bandc.2024.106164

Source: Brain and Cognition - April 26, 2024 Category: Neurology Authors: Brian C Kavanaugh Megan M Vigne Eric Tirrell W Luke Acuff Andrew M Fukuda Ryan Thorpe Anna Sherman Stephanie R Jones Linda L Carpenter Audrey R Tyrka Source Type: research