Abrogating PDK4 activates autophagy-dependent ferroptosis in breast cancer via ASK1/JNK pathway

CONCLUSION: To sum up, deficiency of PDK4 activated ASK1/JNK pathway to stimulate autophagy-dependent ferroptosis in breast cancer.PMID:38678126 | PMC:PMC11055733 | DOI:10.1007/s00432-024-05748-9

Source: Clinical Genitourinary Cancer - April 27, 2024 Category: Cancer & Oncology Authors: Wenbiao Shi Jian Wang Jianbin Chen Xiaoyan Jin Yuanfan Wang Linjun Yang Source Type: research