18. Systematic Organization of Cortical Thickness Co-Alterations in Substance Use Disorders

Previous research has demonstrated systematic structural alterations in neuropsychiatric disorders, linked to the human connectome's intrinsic organization. However, it remains unclear if similar coordinated co-alteration effects extend to substance use disorders (SUDs). Here, we examined substance use co-alteration networks (SUDcov) to uncover macroscale principles of illness and substance-use effects across the cortex.

Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Sofie Valk, Foivos Georgiadis, Meike Hettwer, Sophia Thomopoulos, Paul Thompson, Scott Mackey, Patrica Conrod, Hugh Garavan, Clara Moreau, Boris C. Bernhardt, Matthias Kirschner, ENIGMA Addiction Working Group Source Type: research