268. Subcallosal Cingulate Deep Brain Stimulation for Depression: Long-Term Safety and Effectiveness Outcomes From a Pooled Analysis of 172 Patients

Deep brain stimulation (DBS) has been investigated clinically for treatment-resistant depression (TRD) using various brain targets. Long-term follow-up (LTFU) data from BROADEN, a randomized controlled trial investigating subcallosal cingulate (SCC) DBS for TRD, demonstrated sustained improvement in depressive symptoms, prompting further investigation of DBS as a therapeutic option.

Source: Biological Psychiatry - April 29, 2024 Category: Psychiatry Authors: Lyndahl Himes, Helen Mayberg, Mustafa Husain, Paul Holtzheimer, Andres Lozano, Sidney H. Kennedy, Robert Gross, Brian Harris Kopell, Martijn Figee, Konstantin Slavin, Julie Pilitsis, Joseph Neimat, Clement Hamani, Nader Pouratian, Peter Giacobbe, Alon Mog Source Type: research