489. Deciphering the Molecular Basis of Aging in Substance Use Disorder: Integrative Transcriptomic and Methylomic Analysis
Substance Use Disorder (SUD) contributes to the early onset of age-related diseases and mortality. Although Accelerated Aging (AA) in people with SUD (pSUD) is a key factor in these outcomes, as indicated by changes in Epigenetic Clocks (EC), existing assessments of AA in pSUD primarily utilize ECs designed for non-brain tissues.
Source: Biological Psychiatry - Category: Psychiatry Authors: Bruno Kluwe-Schiavon, Gabriel R. Fries, Laura Stertz, Thomas Meyer, Consuelo Walss-Bass Source Type: research