A PCR-independent approach for mtDNA enrichment and next-generation sequencing: comprehensive evaluation and clinical application

Sequencing the mitochondrial genome has been increasingly important for the investigation of primary mitochondrial diseases (PMD) and mitochondrial genetics. To overcome the limitations originating from PCR-ba...

Source: Journal of Translational Medicine - April 25, 2024 Category: Research Authors: Dong Liang, Lin Zhu, Yuqing Zhu, Mingtao Huang, Ying Lin, Hang Li, Ping Hu, Jun Zhang, Bin Shen and Zhengfeng Xu Tags: Methodology Source Type: research