Association of Interleukin-4 Receptor α Chain I50V Gene Variant (rs1805010) and Asthma in Iranian Population: A Case-control Study

CONCLUSION: Asthma patients have a higher prevalence of the I allele, reflecting the significance of Th2 cells. Although total IgE and IL-17A levels increased in both disease subgroups, total IgE level augmentation correlates directly with disease severity, while IL-17A level enhancement does not.PMID:38660682 | PMC:PMC11037512 | DOI:10.2174/0118743064266613231123103523

Source: Open Respiratory Medicine Journal - April 25, 2024 Category: Respiratory Medicine Authors: Masouma Mowahedi Azam Aramesh Mozhgan Sorkhi Khouzani Marjan Sorkhi Khouzani Saeed Daryanoush Mohammad Samet Morteza Samadi Source Type: research