Tai Chi-induced exosomal LRP1 is associated with memory and hippocampus plasticity in aMCI patients

Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disorder, characterized by aggregation and deposition of amyloid- β (Aβ) peptides in brain1. As an intermediate phase from normal aging to prodromal AD, amnestic mild cognitive impairment (aMCI) is widely recognized as a pivotal stage for early intervention to avoid further cognitive deterioration2,3. It's a high-risk type of MCI that progresses to AD2, typicall y characterized by episodic memory impairment4.

Source: The American Journal of Geriatric Psychiatry - April 25, 2024 Category: Geriatrics Authors: Miaoran Lin, Weilin Liu, Chuyi Ma, Jiahui Gao, Li huang, Jingfang Zhu, Shengxiang Liang, Youze He, Jiao Liu, Jing Tao, Zhizhen Liu, Jia Huang, Zhifu Wang, Lidian Chen Tags: Regular Research Article Source Type: research