PI3K γδ inhibition suppresses key disease features in a rat model of asthma

Two isoforms of Phosphoinositide 3-kinase (PI3K), p110 γ and p110δ, are predominantly expressed in leukocytes and represent attractive therapeutic targets for the treatment of allergic asthma. The study aim was...

Source: Respiratory Research - April 23, 2024 Category: Respiratory Medicine Authors: James W. Pinkerton, Silvia Preite, Antonio Piras, Dimitrios Zervas, Thomais Markou, Mark S. Freeman, Tobias Hofving, Emil Ivarsson, Sara J. Bonvini, Wayne Brailsford, Linda Yrlid, Maria G. Belvisi and Mark A. Birrell Tags: Research Source Type: research