Chemotherapy-elicited extracellular vesicle CXCL1 from dying cells promotes triple-negative breast cancer metastasis by activating TAM/PD-L1 signaling

CONCLUSIONS: Our results highlight CXCL1EV-dead as a novel dying cell-released signal and provide TPCA-1 as a targeting candidate to improve TNBC prognosis.PMID:38654356 | DOI:10.1186/s13046-024-03050-7

Source: Clinical Breast Cancer - April 23, 2024 Category: Cancer & Oncology Authors: Shengqi Wang Jing Li Shicui Hong Neng Wang Shang Xu Bowen Yang Yifeng Zheng Juping Zhang Bo Pan Yudie Hu Zhiyu Wang Source Type: research