lncRNA GAPLINC regulates vascular endothelial cell apoptosis in atherosclerosis

CONCLUSIONS: The present study demonstrates that upregulation of lncRNA GAPLINC represses the binding of miR-183-5p to the PDCD4 promoter region and then promotes PDCD4 expression, thereby inducing cell apoptosis and suppressing endothelial cell proliferation.PMID:38414459 | PMC:PMC10895973 | DOI:10.5114/aoms/169383

Source: Archives of Medical Science - February 28, 2024 Category: Biomedical Science Authors: Jun Pan Bing Wang Xibin Pu Chenyang Qiu Donglin Li Ziheng Wu Honkun Zhang Yangyan He Source Type: research