Arthritis and osteomyelitis in childhood and adolescence-Bacterial and nonbacterial

Z Rheumatol. 2024 Apr 23. doi: 10.1007/s00393-024-01504-z. Online ahead of print.ABSTRACTBacterial arthritis and osteomyelitis are usually acute diseases, which in this way differ from the often insidious course of nonbacterial osteomyelitis; however, there is often an overlap both in less acute courses of bacterial illnesses and also in nonbacterial osteitis. The overlapping clinical phenomena can be explained by similar pathophysiological processes. In bacteria-related illnesses the identification of the pathogen and empirical or targeted anti-infectious treatment are prioritized, whereas no triggering agent is known for nonbacterial diseases. The diagnostics are based on the exclusion of differential diagnoses, clinical scores and magnetic resonance imaging (MRI). An activity-adapted anti-inflammatory treatment is indicated.PMID:38653784 | DOI:10.1007/s00393-024-01504-z

Source: Zeitschrift fur Rheumatologie - April 23, 2024 Category: Rheumatology Authors: T Hospach T Kallinich L Martin T V Kalle F Reichert H J Girschick C M Hedrich Source Type: research